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If your expired pen has lost potency, you're essentially getting a lower dose, which could mean: Worsened blood sugar control if you have diabetes Less weight loss than expected A return of the symptoms that the medication was helping manage For people relying on semaglutide for diabetes management, this reduced effectiveness could be particularly dangerous

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The Registered Human Study ClinicalTrials.gov lists a Phase I safety and pharmacokinetics study under identifier NCT02637284

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