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This makes it a focus in research on fundamental cellular processes rather than just acute energy provision

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Paw withdrawal threshold was calculated from the average of two trials, using SemmesWeinstein von Frey monofilaments with bending forces of 0.008, 0.02, 0.04, 0.07, 0.16, 0.4, 0.6, and 1.0 g) applied in ascending order to the plantar surface

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Biomarker studies have largely focused on diagnostic differentiation 70 , and CSF amyloid- and tau species distinguishing NPH from Alzheimers disease but showing limited specificity for predicting shunt responsiveness 71,72