As of mid-2024, a full 6% of US adults are actively taking GLP-1 agonists , but the huge potential addressable market for these drugs, combined with an ongoing shortage, means that these medications have plenty of additional potential running room
Later on, the FDA approved two other brands with similar formulations to treat obesity and excess weight: Wegovy and Zepbound
Although there is restricted exchange between the cytoplasmic and mitochondrial pools of THF molecules, these compartments are metabolically connected by transport of the one-carbon donors (serine, glycine, and formate) across the mitochondrial membranes
This dual approach is an interesting concept with the ability to not only successfully mediate the harsh microenvironment, but also induce regenerative repair to the damaged site
However, avoid brands making exaggerated "skin whitening" claims the true benefit is structural cellular health and a brighter, natural, even tone