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Originally approved by the FDA to manage type 2 diabetes, semaglutide gained widespread attention when clinical trials showed extraordinary results for weight loss leading to FDA approval specifically for chronic weight management under the brand name Wegovy

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These medications were first used in diabetes management because GLP-1 causes the release of insulin, which helps control blood sugar, says Muhammad Feteiha, MD, general and bariatric surgeon at Atlantic Health System and board certified in Obesity Medicine