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When semaglutide passes its expiration date, several things may happen at the molecular level: Loss of potency: The drug may still appear clear and colorless, but the concentration of active peptide molecules decreases as degradation progresses

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This is quite unbelievable for a condition that could affect around 1 in 11 women in the UK (a widely adopted statistic, but there are no official NHS data to refute or verify this)

Stakeholders and the review panel highlighted several areas for improvement, including two important concerns: lack of an accelerated review option in contrast to other developed NRAs and lack of flexibility in making the assessment commensurate with risk, adequate for the type of product approved or the international approval status