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PMID: 8076778 Ma Q, Lu A.Y.H

Yes, GLP-1 therapy ultimately leads to substantial weight loss, but the process is slower than 1 to 2 pounds per week on average, and success depends on continued use of the medication combined with lifestyle modifications

From a physiological standpoint: No

L-Carnitine is popular in the Muslim gym community for a specific reason: it is marketed as a fat-burning supplement compatible with a cutting phase, and many brothers and sisters use it during Ramadan to support metabolism during fasting periods