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Peak blood levels occur within 24 to 72 hours

Recent trial of proplylactic treatment with T 4 (1.0 ~ 2.0g/Kg/day) for one year in euthyroid patients with Hashimoto's thyroiditis showed decrease of anti-TPO antibodies and thyroid B-lymphocytes(105), suggesting prophylactic T 4 therapy might be useful to stop progression of disease

Journal of the Medical Association of Thailand = Chotmaihet thangphaet

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