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Escalation doses (5mg, 7.5mg, 10mg) Each dose increase can temporarily increase GI sensitivity

They can also worsen blood sugar control in people with type 2 diabetes

Patients considering oral tirzepatide for weight loss program options should understand this distinction and discuss it with their medical provider

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Stomach pain and indigestion Because of slower gastric emptying, Zepbound may lead to stomach pain that feels like cramping or tenderness, says Sowa