L-Carnitine L-Carnitine is an amino acid derivative that shuttles fatty acids into the mitochondria, the energy-producing centers of your cells
For statistical comparisons, two-tailed Students t-tests were employed for two-group comparisons, while one-way or two-way ANOVA with Bonferroni correction was used for comparisons involving three or more groups
FIGURE 2 Patch-clamp studies testing the effects of bath-applied GLP-1 demonstrated that activating the receptor in hippocampal neurons evoked acute membrane potential changes, proving that GLP-1 receptors exist in the hippocampus and can induce acute neuronal changes ( 140 reduced the frequency of miniature inhibitory and excitatory postsynaptic currents (mEPSCs) (mIPSCs) in rat CA1 pyramidal neurons
doi: 10.3389/fendo.2022.846903 Received 31 December 2021 Accepted 01 February 2022 Published 21 February 2022 Volume 13 - 2022 Edited by Paolo Moghetti, University of Verona, Italy Reviewed by Flavia Prodam, University of Eastern Piedmont, Italy Updates Copyright 2022 Cignarelli, Genchi, Le Grazie, Caruso, Marrano, Biondi, DOria, Sorice, Natalicchio, Perrini, Laviola and Giorgino
BPC-157 neuroprotective properties, demonstrated in multiple neurotoxicity models, suggest potential for both prevention and treatment of CIPN