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The lawsuits allege that the drug, which mimics the GLP-1 hormone in the body that aids in insulin secretion, causes severe side effects, including gastroparesis and pancreatic cancer

2017;14(Supplement_5):S35762

These metabolites are capable of exerting passive and active effects on epithelial cells and therefore to overall gut health ( Small molecule hydrophobic metabolites such as propionate, acetate, and butyrate can cross the epithelial barrier by simple diffusion along a concentration gradient from zones of elevated concentration in the intestinal lumen to places of diminished concentration in the epithelial cells (65)

Epp et al

Exenatide had the smallest effect across all of the data analyzed, though it still showed an association with reduced amyloid-beta and tau in some studies