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10.1016/j.phymed.2024.155853 64 KongY.LiuS.WangS.YangB.HeW.LiH.et al (2023a)
For now, they remain completely unproven
10.1016/j.soc.2016.05.009 39
Clinical features of RA primarily include joint swelling, pain, stiffness, weakness, deformity, and fatigue ( Innate immunity plays a critical role in the pathogenesis of RA, including various innate immune cells and components ( The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling pathway is crucial for cells to recognize and respond to cytosolic double-stranded DNA (dsDNA), serving as a primary driver for the establishment of innate immunity through the induction of IFN-I ( 2 An overview of the cGAS-STING signaling pathway The cGAS-STING signaling pathway is widely distributed in immune cells, non-immune cells, tumor cells, and other tissue-derived cells ( cGAS, acts as a cytosolic DNA sensor, recognizing DNA in the cytoplasm that originates from pathogens, mitochondria, micronuclei, and dead cells (3234)
Lastly, incorporating carnitine into a healthy lifestyle, with a balanced diet and regular physical activity, is essential to maximize its effects on weight loss
