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Our findings show that the depletion of GSH by TNBS is a necessary but insufficient event by itself to cause injury

While gastrointestinal AEs such as nausea and vomiting dominate safety reports 8 and recent pharmacovigilance studies highlight increasingly recognized risks including acute pancreatitis, nephritis, hypotension, and syncope 9,10,11 , emerging data suggest that GLP-1 RAs may be associated with neurological adverse events (NAEs) 12,13

Anesthesiology 105:599612

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However, both therapies can increase hepatic workload, requiring baseline liver function assessment and periodic monitoring to ensure safety