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Functional analyses of the gut microbiota in AD patients reveal broad metabolic changes, including alterations in bacterial cell motility, lipoic acid metabolism, and glycan degradation (Ling et al., 2020)

Children (Basel) 2023;10 doi: 10.3390/children10060952

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Sublingual administration, which bypasses the gastrointestinal tract, appears to be equally effective as IM injections while being less invasive and more cost-efficientparticularly in patients with atrophic gastritis, post-gastrectomy status, or conditions that impair intrinsic factor-mediated absorption, where long-term intervention is often required