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As a methoxyindole secreted by the pineal gland, melatonin can increase the number of EPCs and enhance EPCS-mediated angiogenesis by induction HO-1 [132]

Given that gluten peptides are rich in Pro residues too, a dual enzyme therapy combining EP-B2 and prolyl endopeptidase (PEP) has been developed to target both AAs

These observations reinforce the need for well-designed randomised controlled trials (RCTs) to validate the findings and expand the evidence base

Similarly, other studies have reported increased expression of matrix metalloproteinases (MMPs) following exposure to heavy metals

Andreas Michaelides, Head of Psychology at Noom