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Over the last couple of decades, Pratley says, the scientific research community has learned that incretin hormones, including GLP-1, GIP, and others, are important regulators of metabolism with impacts on glycemia, lipids, and body weight

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Since liver ketogenesis is a major source of FGF21 27 , we studied the modulation of this hepatokine by G49 via GCGR based on previous work 28

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