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AMPK activation = increased glucose uptake and fat oxidation Downregulates anabolic processes that consume ATP Promotes mitochondrial biogenesis and cellular resilience MOTSc functions as a mitochondrial-encoded hormone that enhances metabolic flexibility and insulin sensitivity. Lee et al., Cell Metabolism Natural Expression and Peptide Supplementation Your body naturally produces MOTSc, particularly during fasting or exercise

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doi:10.3390/antiox12111953 15

www.loni.ucla.edu/ADNI

Long-term prophylaxis with Lanadelumab led to a significant reduction in attack frequency and severity, improving his quality of life (Figure 1 shows the QoL questionnaire results)