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NHS availability is unlikely before the mid-to-late 2020s at the earliest, as retatrutide must first complete phase 3 trials, receive MHRA marketing authorisation, and undergo a NICE health technology appraisal to assess its clinical and cost-effectiveness

Four of the trials used double-blind, double-dummy methodology

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Having low B12 can cause anaemia, fatigue and a whole host of other things that might make you feel very under the weather