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This interaction site is also occupied by the GS ligand of iron-sulfur clusters that are bound to class II glutaredoxins 7,15,33,5153

L-glutamine is a conditionally essential amino acid, meaning that while our bodies typically produce it, certain situationssuch as intense physical activity, stress, or illnesscan increase the demand for this amino acid

In G6PD-deficient individuals, epithelial and mesenchymal cells such as fibroblasts and lenses, exhibit decreased enzyme activity (102, 103)

The gene expression changes documented in this review occur at the cellular level within hours to days

The linkage between PEG and the drug molecule can be either stable or degradable, the latter being commonly used for prodrugs