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We employed a method that has been reported to measure conformational changes in cell surface receptors, namely trFRET, to investigate the impact of ITP on the conformation of the N-terminal SNAP-tagged version of the IR (Fig

Consistency: Benefits are cumulative

Forouhar F, Lee IN, Vujcic J, Vujcic S, Shen JW, Vorobiev SM, et al

marketed as Mounjaro for T2DM and Zepbound for obesity), is a 39-amino acid peptide acylated with a C20:0 fatty diacid moiety to lysine residue at position 20 with a molecular weight of 4.8 kDa [ Figure 2 , Table 1 ]

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