Lipocalin 2 expression promotes tumor progression and therapy resistance by inhibiting ferroptosis in colorectal cancer
This work was supported by the Japan Society for the Promotion of Science KAKENHI (grant numbers: 16H06403, 16H06400, 16H02666, 16H05377, 20H03604, 23H04173, and 24K02386 to MM), AMED-PRIME (grant number: 21gm6310015h0002 to MM), AMED-CREST (grant numbers: 24gm1510009s0103 and 24gm1910004h0002 to MM), AMED (grant numbers: 21wm04250XXs0101, 21uk1024002h0002, and 25 wm0625510s0102 to MM), and Moonshot R&D (grant number: JPMJMS239F-1-2 to MM)
The CDO products sulphite and CSA are toxic to lung cancer cells
While the approval of Zepbound is a positive advancement, its not the end of CPAPand its not a standalone solution
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