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Phase 3 SYNCHRONIZE trials for obesity fully enrolled (results expected H1 2026)

The active ingredient in both weight loss injections mimics the effects of GLP-1, thereby helping to reduce appetite and calorie intake

Combination with Metformin or Metformin with Sulfonylurea In a 26-week, double-blind trial (Trial 3, NCT02607865), 1864 adult patients with type 2 mellitus diabetes on metformin alone or metformin with sulfonylurea were randomized to RYBELSUS 3 mg, RYBELSUS 7 mg, RYBELSUS 14 mg or sitagliptin 100 mg once daily

Women who are pregnant or breastfeeding

This helps prevent overeating by allowing individuals to recognize when they are full naturally