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Manufacturers now sell directly to patients through platforms like Eli Lilly's LillyDirect and Novo Nordisk's NovoCare, oral GLP-1 options have entered the market, and cash-pay prices have come down significantly from the $1,000-plus list prices of a few years ago

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The appetite arms, GLP-1 and GIP, act largely in the brain and gut, and their satiety effect appears to be amplified in women through the estrogen connection we cover later

Moreover, reimbursement and pricing policies are highly regulated, which drives the market

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