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Important Limitation SURPASS-2 compared tirzepatide against semaglutide 1mg (the Ozempic dose for diabetes), not the higher 2.4mg dose used for weight loss (Wegovy)

Total and appendicular lean body mass, total fat mass, and android fat mass were also assessed by DXA, which measures changes in body composition over time and has been commonly used in other clinical research studies, enabling a comparison with efficacy measures in other published studies 19,27