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While the buttocks have adequate subcutaneous tissue, the difficulty of self-injection in this area and the lack of clinical data supporting this site mean it is not recommended

Always reconstitute with bacteriostatic water and dose subcutaneously

In contrast, SMOTE-ENN demonstrated consistent performance across 5-CV and independent validation, highlighting its robustness and ability to generalize effectively

10.1016/j.neurobiolaging.2015.10.004 Neurobiol