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We also recently reported association studies between specific cecal microbial taxa and plasma BB concentrations in mice (26)

Aug 2007;193(2):277-82

& Wadden, T

Conversely, the notable elevation of hexanoate in fasted Pcca -/- (A138T) mice corroborates heightened fatty acid oxidation during fasting, as hexanoate is derived from the hydrolysis of hexanoyl-CoA 45

While a number of Nrf2 inducers have been developed and tested in clinical trials (Pergola et al., 2011