why does glp 1 cause weight loss and Maintenance Related to the Mechanism of Action of Glucagon-Like Peptide Receptor Agonists Adverse effects of GLP-1 class

Salehi, B., Ylmaz, Y

Animals were fasted for 2 hours prior to intraperitoneal injection of glucose (2 g/kg) +/- exendin-4 (1 nmol/kg) and continued to fast for 6 hours when blood glucose levels were assessed from the tail vein using a Contour glucometer (Bayer) and strips at 0-, 10-, 30-, and 60-minute time-points, with glucose response curves generated from these data

O.TokumaruY.LeeJ.RatovitskiE.SidranskyD.et al (2004)

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The biology is complex, and that GLP-1 receptor in the body is not only controlling one thing or doing one thing, but has an intricate web of various effects. This article is exclusive to STAT+ subscribers Unlock this article plus in-depth analysis, newsletters, premium events, and news alerts