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MTHFR, or the methylenetetrahydrofolate reductase is the key regulatory enzyme in folate and homocysteine metabolism

S-Acetyl-Glutathione is known as the master antioxidant and is highly active in human lungs and many other organ systems and tissues

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GPx1 achieves its function by using two molecules of glutathione as cofactors which are ultimately reduced to glutathione disulfide in a two-step process [10]

Metabolomic pathway analysis demonstrated that these metabolites are involved in sulfurate amino acids metabolism, with respect to cysteine, and glutathione synthesis (Fig