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Curtis, PhD Departments of Population Health Sciences and Medicine, Duke University School of Medicine , Durham, NC,, Ania Jastreboff, MD, PhD Y-Weight Yale Obesity Research Center, Section of Endocrinology and Metabolism, Department of Medicine, Yale School of Medicine , New Haven, CT Section of Pediatric Endocrinology, Department of Pediatrics, Yale School of Medicine , New Haven, CT, Yuan Lu, PhD Center for Outcomes Research and Evaluation, Yale New Haven Hospital , New Haven, CT Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine , New Haven, CT Department of Biomedical Informatics and Data Sciences, Yale School of Medicine , New Haven, CT,Nicholas Stucky, MD, PhD Truveta, Inc , Bellevue, WA In March 2024, the U.S
A hyperglycemic clamp with GIP and GLP-1 infusion was performed before and after intensive insulin treatment
The test analyzes key genetic variants including GLP1R rs6923761, GIPR rs1800437, FTO rs9939609, and MC4R rs17782313 across 14 metabolic pathways and 49 peptides