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doi: 10.1192/j.eurpsy.2025.10125 Summary Keywords dopamine, GABA, ghrelin, GLP-1 RA, inflammation, leptin, suicidality Citation Borovcanin MM and Petrovic I (2026) Suicidality as a potential risk and therapeutic target during widespread GLP-1 receptor agonists use: implications of inflammation

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Adding GIP receptor (GIPR) agonism introduces a second incretin pathway that enhances insulin secretion through distinct cAMP signaling, independently modulates adipocyte lipid handling, and engages central appetite circuits through complementary routes to GLP-1R

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