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On the other hand, major pathological changes in PD include abnormal mitochondrial dysfunction, protein aggregation, oxidative stress, glutamate toxicity, calcium overload, and neuroglial dysfunction

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Environ Pollut 225:559568 Yang JF, Ying GG, Zhao JL, Tao R, Su HC, Chen F (2010) Simultaneous determination of four classes of antibiotics in sediments of the Pearl Rivers using RRLC-MS/MS