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While the cited articles provide valuable insights, their mechanistic and clinical heterogeneities highlight the need for a more standardized and pathway-centric approach in this field

This helps prevent pathogen attachment and reduces liver damage caused by the production of endotoxins and other toxic compounds by bacteria ( In the present study, the effects of diarrhea with kidney-yang deficiency syndrome on the gut microbiota were found to be consistent with previous findings in diarrhea cases

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Data availability The dataset supporting the conclusions of this article is available in the SRA repository [ information is available in the Additional files 1 to 4