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Elevated levels of anti-nuclear/extractable-nuclear antibodies are strongly correlated with higher level of TNF- and are linked to fatigue in various diseases including chronic fatigue syndrome and rheumatoid arthritis (38)

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Lau J, Bloch P, Schaffer L, et al

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References Badenhorst, T., Svirskis, D., Wilsher, T., & O'Sullivan, J

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