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Mitochondrial Origin = Metabolic Power Unlike typical peptides, MOTSc is synthesized in response to cellular energy demandsparticularly when glucose is scarce or when the body is under stress

After undergoing magnetic stirring for 8 h at room temperature, mPEG 5000 -OH (0.68 g, 0.13 mmol) was introduced into the reaction system

Mtb infection of macrophages resulted in decreased levels of GSH and GPX4, increased free iron, mitochondrial superoxide, and lipid peroxidation

(Thng 5-6 nm 2016)

This modification allows researchers to study prolonged activity and sustained interaction within controlled laboratory conditions