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Se cree que podra deberse a efectos asociados a la diuresis osmtica, lo que explicara la disminucin de IC y sus complicaciones asociadas que parecen dar cuenta de los mayores beneficios del estudio123

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This is an important treatment aspect, as weight reduction most likely plays an important role in the prevention and reduced progression of CKD, an association demonstrated in people with macroalbuminuria having undergone bariatric surgery [115]

Reeves and Hoffmann, 2009