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Conclusion: AOD 9604 dose dependently increases bone density, improves bone microstructure, enhances bone strength, and reverses bone metabolism imbalance in postmenopausal osteoporotic rats

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The role of prostaglandin E2 (PGE2), the third main prostaglandin, in adipogenesis is controversial as PGE2 exhibits antilipolytic effect in mature adipocytes but shows no effect on preadipocytes [170]