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Long-term hyperglycemia can contribute to persistent disturbances in glutamatergic signaling and neural damage in the medial prefrontal cortex, contributing to depressive behaviors [91]

Mounjaro and Zepbound also mimic GLP-1, along with a related hormone called glucose-dependent insulinotropic peptide, or GIP

10.1002/jbmr.3706 48 PatelM

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