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The molecular structure of GHK-Cu features a tripeptide sequence (Gly-His-Lys) with high affinity for copper(II) ions, forming a stable 1:1 complex with a dissociation constant in the nanomolar range

Frag 176-191 is not currently listed on the WADA Prohibited List as of 2026

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A systematic review of the relevant literature, summarized herein, indicates that this chronotherapeutic hypothesis is unaddressed within the clinical literature on antioxidant therapy for brain disorders such as schizophrenia