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In the five in vitro studies, although a decrease in the apoptosis rate of granulosa cells was observed at specific doses, it was not confirmed whether this effect could translate into an improvement in oocyte quality in vivo (Fabov et al., 2023

The glycocalyx on the endothelial cell surface regulates cell adhesion, anticoagulation, vascular permeability, mechanoreception, and mechanotransduction [8, 9]

The emergence of GLP-1 receptor agonists, such as the first clinically approved agonist, exenatide, in 2005, paved the way for the thorough exploration of these molecules [12]