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In asymptomatic patients with risk factors (see Table 1: Patient Risk Factors Associated with B 12 Deficiency below) consider supplementation in lieu of testing

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The central reason for these symptoms is poor nutrient stores, which are not fixed by empty calories from sugar and caffeine

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(iii) Epigenetic regulation: Butyrate acts as a histone deacetylase (HDAC) inhibitor, influencing neuronal gene expression with implications for learning, memory, and neuroprotection (Duranti et al., 2020)

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