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Medical Management a) Anticonvulsants First-line treatment to calm overactive nerves: Carbamazepine (most effective) Oxcarbazepine , Gabapentin , Pregabalin , Phenytoin b) Muscle Relaxants Baclofen is often added when anticonvulsants alone are insufficient

This can lead to improved sleep quality, reduced discomfort, and an overall enhanced sense of well-being

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These treatments have generated blockbuster revenue for the companies, and rivals, from biotech Viking Therapeutics to pharma giant Pfizer , are developing candidates and hope to eventually join them in this valuable market -- one forecast to approach $100 billion by the end of the decade

Post-exercise recovery : Supplementing with L-Carnitine has been found to reduce muscle damage, inflammation, and soreness that can occur after intense workouts