Damaged intestinal barrier can facilitate the development of local diseases such as irritable bowel disease, inflammatory bowel disease or celiac disease, but also the development of systemic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, hepatitis, and lupus erythematosus, neurodegenerative or psychiatric conditions, or metabolic diseases such as diabetes or obesity
Non-surgical weight loss is usually a safer option for patients, and it is typically recommended to try non-surgical aids and healthy weight loss methods before considering a surgical procedure for weight loss
In reality, thats only partly true
Gut and inflammation: Individuals with persistent digestive discomfort where gut barrier support is clinically relevant, people with suspected gut-inflammation overlap contributing to fatigue or poor systemic recovery, and those with a history of NSAID-related gut irritation
doi: 10.1016/j.cell.2023.09.013 6 WolfeFRussellIVipraioGRossKAndersonJ