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However, substantial heterogeneity among studies was observed, likely attributable to differences in dosage, baseline B12 status, and population characteristics

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3.2 Quality and risk of bias assessment After critical appraisal using the CASP checklists and NewcastleOttawa Scale, the majority of included studies were assessed as moderate to high quality

Since the diagnosis and treatment of Graves disease are not as straightforward as one might think, many patients are treated without giving them a complete and necessary rundown of the potential risks and benefits of therapy

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