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This makes them slower acting, particularly for anyone with gut absorption issues
The SURPASS-CVOT trial (NCT04255433) will assess the cardiovascular safety of tirzepatide compared to dulaglutide in people with T2D and established atherosclerotic disease [111]
In addition, in BPC 157 short-bowel rats, the counteraction of the escalating short bowel syndrome provides that all three intestinal wall layers accordingly adapt in parallel with reaching the same weight gain as in normal rats (Sever et al., 2009) (see Fistula Healing as Support )
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