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Early life and education [edit] Attia was born and raised in Toronto, Ontario, Canada

[DOI] [PubMed] [Google Scholar] 197.Dormandy JA, Charbonnel B, Eckland DJA et al (2005) Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

however, it is not known whether this occurs at clinically relevant doses in humans

Remarkably, HDL prevents the oxidation of LDL (Figure 10) and recent evidence suggests that this may occur through 4 distinct proteins circulating on HDL apoA-I (845,846), LCAT (847), lipoprotein-associated phospholipase A2 (Lp-PLA2)(848,849), and paraoxonase 1 (PON1) (430,846)