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The compound has been shown in cell-based research to upregulate VEGFR2 transcript levels, increase phosphorylation of downstream signalling intermediates after VEGF stimulation, and enhance endothelial tube formation in matrigel assays

Evidence for Increased Catabolism of Vitamin B-6 during Systemic Inflammation. The American Journal of Clinical Nutrition, vol

J Clin Endocrinol Metab 77:273280 Bianda T, Glatz Y, Bouillon R, Froesch ER, Schmid C (1998) Effects of short-term insulin-like growth factor-I (IGF-I) or growth hormone (GH) treatment on bone metabolism and on production of 1,25-dihydroxycholecalciferol in GH-deficient adults

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