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Van Dat B, Van Hieu JJ, Sol D, Jungmi S, Farrokhroo L, Chan Ho G, Yu Jin K, Won-Kyo J, Wooram J, Hyung U
Additionally, there is tirzepatide, which is a fusion of GLP-1s and an additional hormone called gastric inhibitory polypeptide (GIP)
This step establishes the baseline chemical environment required to keep GSH reduced
The clinical significance of the comparison is most relevant for patients who have already been on semaglutide or tirzepatide: for these patients, retatrutide offers a mechanistic step up rather than simply a higher dose of the same class