Its cyclic peptide structure provides enhanced receptor-binding stability and resistance to enzymatic degradation, making it particularly useful for mechanistic investigations involving receptor selectivity and signaling kinetics
Besides promoting the release of insulin, GLP-1 also suppresses the secretion of glucagon and reduces appetite
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Different from GSH-TPGS, GSH-PEG employed GSHs thiol group ( S -terminal) for linkage to PEG to form a thioether bond instead of an ester bond derived from the C -terminal linkage of the glycine carboxylic acid in GSH-TPGS
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