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Its antioxidant activity comes from the reactive thiol group on its cysteine residue, which donates electrons to neutralize reactive oxygen species and serves as a substrate for protective enzymes like glutathione peroxidase

In patients with RA remission, the level of phosphatidyl acid (PA(28:0)) in synovial fluid significantly increased, which stabilized SCAP-SREBP complex on the endoplasmic reticulum by binding to Insig protein, and inhibited the expression of HMGCR, a key enzyme in cholesterol synthesis (76, 78, 79)

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