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A 2023 study found that regular e-cigarette use predicted worsening symptoms of depression, anxiety, and social dysfunction over time.20 This aligns with findings from a 2020 systematic review, which concluded that the relationship between vaping and mental health is bidirectional: adolescents with pre-existing anxiety or depression are more likely to vape, but vaping itself can increase the risk of mental health deterioration.21 Risky ingredients in vapes A growing body of research shows that e-cigarette aerosols contain carcinogenic and toxic substances, including formaldehyde a chemical traditionally used to preserve biological specimens as well as acrolein (a highly toxic and corrosive substance) and heavy metals like lead, nickel, and tin.3 29 30 Scientists have detected these compounds in vape emissions, raising serious concerns about long-term exposure

Jane Fonda had secured the rights to the play of the same name from Ernest Thompson (who also wrote the screen play), the relationship in the film mirroring that of the two Fondas

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