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The principal investigator for the study, Professor Carel le Roux (University College Dublin), highlighted that, by activating both the GLP-1 receptor and glucagon receptor, survodutide may both inhibit appetite and improve energy expenditure. Oral semaglutide for weight loss: OASIS 1 trial Oral semaglutide is used at doses of 7 mg and 14 mg daily for glucose-lowering treatment in people with type 2 diabetes

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In particular, researchers are focused on whether medications that influence appetite and metabolic signaling may also affect pathways involved in craving, motivation, and reinforcement

The European Medicines Agency's European Public Assessment Report (EPAR) for Ozempic provides additional context from the clinical development programme